selected publications
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academic article
- First intramolecular Diels–Alder reactions using chromone derivatives: synthesis of chromeno[3,4-b]xanthones and 2-(benzo[c]chromenyl)chromones. New Journal of Chemistry. 2018
- Simultaneous characterization and quantification of phenolic compounds in Thymus x citriodorus using a validated HPLC-UV and ESI-MS combined method. Food Research International. 54:1773-1780. 2013
- Six-membered ring systems. With O and/or S atoms.. Progress in Heterocyclic Chemistry. 25:406-453. 2013
- Identification of phenolic constituents of Cytisus multiflorus. Food Chemistry. 131:652-659. 2012
- Hepatoprotective activity of polyhydroxylated 2-styrylchromones against tert-butylhydroperoxide induced toxicity in freshly isolated rat hepatocytes. Archives of Toxicology. 77:500-505. 2003
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book
- Six-Membered Ring Systems: With O and/or S Atoms. Ed. 27. 2015
- Six-membered ring systems: With O and/or S atoms. Ed. 26. 2014
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chapter
- Six-membered ring systems: With O and/or S atoms. Progress in Heterocyclic Chemistry. 493-568. 2024
- Six-membered ring systems: With O and/or S atoms. Progress in Heterocyclic Chemistry. 487-557. 2023
- Cholesterol chemistry and laboratory synthesis. 3-24. 2022
- Eight-Membered Rings With One Oxygen Atom. 44-84. 2022
- Recent advances in the synthesis of 4H-chromen-4-ones (2012 - 2021). 159-241. 2022
- Six-membered ring systems: with O and/or S atoms. Progress in Heterocyclic Chemistry. 473-532. 2021
- Six-membered ring systems: with O and/or S atoms. 533-595. 2020
- Six-membered ring systems: with O and/or S atoms. 427-491. 2018
- Six-Membered Ring Systems: With O and/or S Atoms. 519-578. 2017
- Valuable analytical tools in analysis of honeybee plant-derived compounds: nuclear magnetic resonance spectroscopy. 150-195. 2016
- Nuclear magnetic resonance spectroscopy for structural characterization of bioactive compounds. 149-192. 2014
- Six-membered ring systems: with O and/or S atoms. 443-492. 2012
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conference paper
- Analysis of the antidiabetic potential of natural xanthones through the inhibition of a-amylase and a-glucosidase activities 2022
- Analysis of the antidiabetic potential of natural xanthones through the inhibition of α-amylase and α-glucosidase activities. 57-57. 2022
- Inhibition of pancreatic a-amylase activity by a group of hydroxyxanthones 2020
- Inhibition of pancreatic α-amylase activity by a group of hydroxyxanthones. 66-66. 2020
- Modulating protein aggregation in cell models using modified steroids. 66. 2019
- Synthesis and in vitro a-glucosidase inhibitory activity of polyhydroxylated 2-styrylchromones 2019
- Synthesis and in vitro α-glucosidase inhibitory activity of polyhydroxylated 2-styrylchromones. 68. 2019
- Atividade antimicrobiana de duas espécies de Salvia: S. elegans e S. officinalis 2018
- Design, synthesis and preliminar antioxidant evaluation of new hydroxy- chromone and xanthone derivatives. 46. 2018
- Evaluation of in vitro anti-diabetic potential of 2, 3-diaryb(anthones through the inhibition of a-glucosidase. 343. 2018
- Chemical characterization of three Thymus species: T. herba-barona, T. pseudolanuginosus and T. caespititius. 72. 2017
- Chromones as versatile building blocks in cycloaddition reactions. 233. 2017
- Conjugate additions of carbon nucleophiles to chromone derivatives towards nitrogen heterocycles 2017
- Conjugate additions of carbon nucleophiles to chromones substituted with extended p-systems at C-2 2017
- Conjugate additions of carbon nucleophiles to chromones substituted with extended π-systems at C-2. 128. 2017
- Microwave-assisted synthesis of chromeno[3,4-b]xanthones and (benzo[c]cromenyl)chromones. 118. 2017
- Nitromethane conjugate addition to 2-[(1E,3E)-4-arylbuta-1,3-dien-1-yl]-4H-chromen-4-ones 2017
- Nitromethane conjugate addition to 2-[(1E,3E)-4-arylbuta-1,3-dien-1-yl]-4Hchromen- 4-ones 2017
- Phytochemicals of Salvia africana and Salvia elegans and Salvia officinalis 'Icterina'. 73-73. 2017
- Phytochemicals of Salvia africana, Salvia elegans and Salvia officinalis 'Icterina' 2017
- 2-[(1E,3E)-4-Arylbuta-1,3-dien-1-yl]-4H-chromen-4-ones as dienes in Diels–Alder reactions: experimental and computational studies 2016
- Arylxanthones with anti-inflammator potential in cellular systems 2016
- Chromone derivatives as novel dienes in Diels-Alder reactions 2016
- Recent developments in the synthesis of novel xanthone-1,2,3-triazole dyads 2015
- Synthesis of xanthone-1,2,3-triazole dyads 2015
- The antioxidant activity of novel chromones and xanthones: a structure-activity relationship 2015
- 2-(4-Arylbuta-1,3-dien- or 1-en-3-yn-1-yl)chromones as synthons for the synthesis of other nitrogen and oxygen heterocyclic compounds 2014
- Propriedades nutricionais e bioativas do cultivar de colza Hydromel. 157. 2014
- Síntese de novas cromonas e xantonas com atividade captadora de espécies reativas de oxigénio. 384. 2014
- Synthesis of (E)-2-(4-Arylbut-1-en-3-ynyl)-4H-chromen-4-ones. 63. 2013
- Synthesis of 2-{2-[5(4)-aryl-2H-[1,2,3]-triazol-4(5)-yl]vinyl}chromen-4-ones. 103. 2013
- The response of rapeseed cultivar hydromel to nitrogen fertilization: chemical composition and antioxidant capacity. 230. 2013
- Cytisus multiflorus: phenolic characterization by HPLC-DAD, ESI-MSn and NMR combined methods. 131. 2012
- Cytisus multiflorus: source of antioxidant polyphenols 2012
- Efeito da adubação azotada na composição química de sementes de colza da cultivar hydromel 2012
- Electrochemical behavior of Hydroxyxanthones versus ROS scavenging activities 2012
- Electrochemical characterization of hydroxylated xanthones by cyclic voltammetry 2012
- New syntheses of novel arylxanthones 2012
- Novel flavones in Lamium L. genus 2012
- Phenylethanoids and isoscutellarein derivatives from Lamium album L. 2012
- Polyhydroxylated 2-styrylchromones and –xanthones as potent antioxidante agentes 2012
- Structure determination of some oxygen and nitrogen heterocyclic compounds by NMR 2012
- Synthesis of Benzo[a]naphtho[2,3-c]xanthones from 2-styrylchromones 2012
- Synthesis of novel 2-Butadienylchromone derivatives 2012
- Novel Hydroxy-9H-xanthen-9-ones derivatives: synthesis and bioactive properties 2011
- Unusual flavones in cytisus desf.. Planta Medica. 1352-1352. 2011
- Metodologias para avaliar a actividade captadora de espécies reactivas de oxigénio e de azoto envolvidas no processo inflamatório 2010
- NDPO2 as a selective generator of 1o2 used in the scavenging activity assay of 2,3-diarylxanthones 2010
- ROS and RNS Scavenging Activity by 2,3-Diarylxanthones 2010
- Recent developments in the synthesis of 1-aryl-9H-xanthen-9-ones 2010
- Studies towards the synthesis of polyhydroxyxanthones with potential antioxidant activity 2010
- The 2-styrylchromone structure is an effective scaffold for the development of new inibitors of the nf-kb pathway 2010
- Anti-inflammatory potencial of 2-Styrylchromones regarding their interference with arachidonic acid metabolic pathways 2008
- Cyclic voltammetric analysis of 2-styrylchromones 2008
- Incorporation of 2-styrylchromones in liposomes: preliminaries studies 2008
- Novel 2-Styrylchromones with high anti-inflammatory potencial through prevention of LTB4 production by human leukocytes, inhibition of COX-1 activity and scavenging of ROS and RNS 2008
- Polyhydroxy-2,3-diarylxanthones as antioxidants 2008
- The ROS and RNS scavenging activity of 2-Styrylchromones are effectively repreoduced by cyclic voltammetry analysis 2008
- Inhibition of Leukotriene B4 production in human Neutrophils by 2-Styrylchromones 2007
- Interactions of 2-Styrylchromones with pro-inflamatory enzymes and oxidative species 2007
- Polyhydroxy-2,3-Arylxanthones: a total synthesis 2007
- A novel route for the synthesis of 2,3-Diarylxanthones 2006
- Epoxidation of (E,E)-Cinnamylideneacetophenones Using Salen Mn(III) as Catalyst 2006
- NMR in the epoxidation of (E,E)-Cinnamylideneacetophenones 2006
- Singlet oxygen scavenging activity by 2-Styrylchromones 2006
- Synthesis of 2,3-Arylxanthones using palladium catalysts 2006
- Synthesis of Polyhydroxy-2,3-diarylxanthones with potencial antioxidant activity 2006
- Nitric oxide and superoxide radical scavenging of 2-Styrylchromones 2005
- Synthesis of 2,3-Distyrylchromones 2005
- Synthesis of new xanthone derivatives 2005
- Epoxidation of 2-Styrylchromone derivatives 2004
- Epoxidação de (E,E)-Cinamilidenoacetofenonas com Peróxido de Hidrogénio 2004
- Epoxidation Studies do 2-Styrylchromones 2003
- Hepatoprotective activity of 2-styrylchromone derivatives against the pro-oxidant hepatotoxic effect elicited by tert-butylhydroperoxide in freshy isolated rat hepatocytes 2003
- Potent Inhibition of Xanthine Oxidase by Novel 2-Styrylchromones 2001
- 2-Styrylchromones with potencial antioxidant activity 2000
- NMR studies on the antiradical mechanism of phenolic compounds towards 2,2-diphenil-1-pycridrazyl radical 2000
- Synthesis and evaluation of the antiradicalar activity of polyhydroxy-2-styrylchromones 2000
- Synthesis of 2-styrylchromones with potencial antioxidant activity 1999
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document
- Indoor and Outdoor Air Pollution in Bragança: Causes, Inhalation Exposure and Toxicity 2022
- Atividade antimicrobiana de duas espécies de Salvia: S. elegans e S. officinalis 2018
- Chemical characterization of three Thymus species: T. herba-barona, T. pseudolanuginosus and T. caespititius 2017
- Phytochemicals of Salvia africana and Salvia elegans and Salvia officinalis 'Icterina' 2017
- Phytochemicals of Salvia africana, Salvia elegans and Salvia officinalis 'Icterina' 2017
- Simultaneous characterization and quantification of phenolic compounds in Thymus x citriodorus using a validated HPLC-UV and ESI- MS combined method 2013
- Cytisus multiflorus: phenolic characterization by HPLC-DAD, ESI-MSn and NMR combined methods 2012
- Cytisus multiflorus: source of antioxidant polyphenols 2012
- Novel flavones in Lamium L. genus 2012
- Phenylethanoids and isoscutellarein derivatives from Lamium album L. 2012
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journal article
- Steroid–Quinoline Hybrids for Disruption and Reversion of Protein Aggregation Processes. ACS Medicinal Chemistry Letters. 443-448. 2022
- Inhibition of the carbohydrate-hydrolyzing enzymes a-amylase and a-glucosidase by hydroxylated xanthones. Food & Function. 7930-7941. 2022
- Hemi-synthesis of novel (S)-carvone hydrazone from Carum carvi L. essential oils: Structural and crystal characterization, targeted bioassays and molecular docking on human protein kinase (CK2) and Epidermal Growth factor Kinase (EGFK). Journal of Molecular Structure. 1-13. 2021
- Antioxidant Adjustments of Olive Trees (Olea Europaea) under Field Stress Conditions. Plants. 684-684. 2021
- The Antioxidant Activity of Prenylflavonoids. Molecules. 696. 2020
- Phytochemical Composition and Bioactive Effects of Salvia africana, Salvia officinalis ‘Icterina’ and Salvia mexicana Aqueous Extracts. Molecules. 2019
- The Health-Benefits and Phytochemical Profile of Salvia apiana and Salvia farinacea var. Victoria Blue Decoctions. Antioxidants. 1-14. 2019
- A study towards drug discovery for the management of type 2 diabetes mellitus through inhibition of the carbohydrate-hydrolyzing enzymes a-amylase and a-glucosidase by chalcone derivatives. Food & Function. 5510-5520. 2019
- Cholesterol-Based Compounds: Recent Advances in Synthesis and Applications. Molecules. 2019
- Metabolites and Biological Activities of Thymus zygis, Thymus pulegioides, and Thymus fragrantissimus Grown under Organic Cultivation. Molecules. 1-15. 2018
- First intramolecular Diels-Alder reactions using chromone derivatives: Synthesis of chromeno[3,4-: B] xanthones and 2-(benzo [c] chromenyl)chromones. New Journal of Chemistry. 2018
- Salvia elegans, Salvia greggii and Salvia officinalis Decoctions: Antioxidant Activities and Inhibition of Carbohydrate and Lipid Metabolic Enzymes. Molecules. 1-17. 2018
- 1,6-Conjugate Additions of Carbon Nucleophiles to 2-[(1E ,3E )-4-Arylbuta-1,3-dien-1-yl]-4H -chromen-4-ones. European Journal of Organic Chemistry. 5293-5305. 2017
- Health-Promoting Effects of Thymus herba-barona, Thymus pseudolanuginosus, and Thymus caespititius Decoctions. International Journal of Molecular Sciences. 1879. 2017
- An Overview of 2-Styrylchromones: Natural Occurrence, Synthesis, Reactivity and Biological Properties. European Journal of Organic Chemistry. 3115-3133. 2017
- 2-[(1E ,3E )-4-Arylbuta-1,3-dien-1-yl]-4H -chromen-4-ones as Dienes in Diels-Alder Reactions - Experimental and Computational Studies. European Journal of Organic Chemistry. 87-101. 2017
- 2,3-Diarylxanthones as potential inhibitors of Arachidonic acid metabolic pathways. Inflammation. 956-964. 2017
- Synthesis of chromone-related pyrazole compounds. Molecules. 2017
- Arylxanthones and arylacridones: A synthetic overview. Pure and Applied Chemistry. 579-594. 2016
- Characterization of 2,3-diarylxanthones by electrospray mass spectrometry: gas-phase chemistry versus known antioxidant activity properties. Rapid Communications in Mass Spectrometry. 2228-2236. 2016
- Novel chromone and xanthone derivatives: Synthesis and ROS/RNS scavenging activities. European Journal of Medicinal Chemistry. 381-392. 2016
- (E)-2-(4-Arylbut-1-en-3-yn-1-yl)chromones as Synthons for the Synthesis of Xanthone-1,2,3-triazole Dyads. European Journal of Organic Chemistry. 4732-4743. 2015
- Inhibition of NF-kB Activation and Cytokines Production in THP-1 Monocytes by 2-Styrylchromones. Medicinal Chemistry. 560-566. 2015
- Seaweeds as preventive agents for cardiovascular diseases: from nutrients to functional foods. Marine Drugs. 6838-6865. 2015
- Chalcones as versatile synthons for the synthesis of 5- and 6-membered nitrogen heterocylces. Current Organic Chemistry. 2750-2775. 2014
- Synthesis and transformation of halochromones. Current Organic Synthesis. 317-341. 2014
- Electrochemical characterization of bioactive hydroxyxanthones by cyclic voltammetry. Tetrahedron Letters. 85-90. 2013
- Simultaneous characterization and quantification of phenolic compounds in Thymus x citriodorus using a validated HPLC-UV and ESI- MS combined method. Food Research International. 1773-1780. 2013
- Identification of phenolic constituents of cytisus multiflorus. Food Chemistry. 652-659. 2012
- Phenolic constituents of Lamium album: Focus on isoscutellarein derivatives. Food Research International. 330-335. 2012
- Synthesis and structure elucidation of novel pyrazolyl-2-pyrazolines obtained by the reaction of 3-(3-aryl-3-oxopropenyl)chromen-4-ones with phenylhydrazine. Arkivoc. 265-281. 2012
- Tetrahydroquinazoline-substituted chromones from Diels-Alder reaction of (E)-2-styrylchromones and pyrimidine ortho-quinodimethane. Tetrahedron Letters. 2722-2725. 2012
- The dependence of a-tocopheroxyl radical reduction by hydroxy-2,3-diarylxanthones on structure and micro-environment. Organic and Biomolecular Chemistry. 2068-2076. 2012
- Structure-activity relationships in hydroxy-2,3-diarylxanthone antioxidants. Fast kinetics spectroscopy as a tool to evaluate the potential for antioxidant activity in biological systems. Organic and Biomolecular Chemistry. 3965-3974. 2011
- Synthesis of Novel 1-Aryl-9H-xanthen-9-ones. Synlett. 1403-1406. 2011
- 2,3-Diarylxanthones as strong scavengers of reactive oxygen and nitrogen species: A structure-activity relationship study. Bioorganic & Medicinal Chemistry. 6776-6784. 2010
- Anti-inflammatory potential of 2-styrylchromones regarding their interference with arachidonic acid metabolic pathways. Biochemical Pharmacology. 171-177. 2009
- Dimethyldioxirane oxidation of exocyclic (E,E)-cinnamylideneketones. Australian Journal of Chemistry. 82-89. 2009
- Efficient syntheses of new polyhydroxylated 2,3-diaryl-9H-xanthen-9-ones. European Journal of Organic Chemistry. 2642-2660. 2009
- Cyclic voltammetric analysis of 2-styrylchromones: Relationship with the antioxidant activity. Bioorganic & Medicinal Chemistry. 7939-7943. 2008
- 2-Styrylchromones: Novel strong scavengers of reactive oxygen and nitrogen species. Bioorganic & Medicinal Chemistry. 6027-6036. 2007
- A novel and efficient route for the syntheses of hydroxylated 2,3-diarylxanthones. Synlett. 3113-3116. 2007
- Epoxidation of (E,E)-cinnamylideneacetophenones with hydrogen peroxide and iodosylbenzene with salen-MnIII as the catalyst. European Journal of Organic Chemistry. 2877-2887. 2007
- Epoxidation studies of 2-styrylchromones using Jacobsen's catalyst and hydrogen peroxide and iodosylbenzene as oxidants. Journal of Heterocyclic Chemistry. 1319-1326. 2006
- New Synthesis of 2,3-Diarylxanthones. Synlett. 3095-3098. 2005
- Hepatoprotective activity of polyhydroxylated 2-styrylchromones against tert-butylhydroperoxide induced toxicity in freshly isolated rat hepatocytes. Archives of Toxicology. 500-505. 2003
- Synthesis of New Hydroxy-2-styrylchromones. European Journal of Organic Chemistry. 4575-4585. 2003
- 2-Styrylchromones as novel inhibitors of xanthine oxidase. A structure-activity study. Journal of Enzyme Inhibition and Medicinal Chemistry. 45-48. 2002