Synthesis of 2-{2-[5(4)-aryl-2H-[1,2,3]-triazol-4(5)-yl]vinyl}chromen-4-ones
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abstract
Chromones are a family of oxygen-containing heterocyclic compounds that have been
shown particular relevant biological activity. In what concerns to 2-methylchromones, their
reactivity is well-known and allowed to exploit many different kinds of chemical reactions.
The acidic character of the 2-methyl group, due to the low electron density at C-2 caused by
carbonyl group enable this class of compounds to undergo oxidation, photolysis,
cycloaddition and condensation reactions
University of Aveiro, Funda9ao para a Ciencia e Tecnologia
(FCT, Portugal), European Union, QREN, FEDER and COMPETE for funding the QOPNA Research Unit
(project PEst-C/QUI/UI0062/2011) and the Portuguese National NMR Network. Hello Albuquerque also
thanks FCT for his fellowship (SFRH/Bl/51556/2011 ).
University of Aveiro, Funda9ao para a Ciencia e Tecnologia
(FCT, Portugal), European Union, QREN, FEDER and COMPETE for funding the QOPNA Research Unit (project PEst-C/QUI/UI0062/2011) and the Portuguese National NMR Network. Hello Albuquerque also thanks FCT for his fellowship (SFRH/Bl/51556/2011 ).