publicações selecionadas
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artigo de revista
- In Silico Identification of Six Mushroom-Derived Sterol and Triterpenoid Compounds as Potential P-Glycoprotein Modulators in Multidrug Resistance. Applied Sciences. 2025
- Blockchain revolution in food supply chains: A positive impact on global food loss and waste. Food Chemistry. 2025
- Evaluation of berberine nanoparticles as a strategy to modulate acetylcholinesterase activity. Food Research International. 2023
- Encapsulation of Sorghum Leaf Red Dye: Biological and Physicochemical Properties and Effect on Stability. Foods. 2023
- Fig Leaves (Ficus carica L.): Source of Bioactive Ingredients for Industrial Valorization. Processes. 2023
- Natural Food Colorants and Preservatives: A Review, a Demand, and a Challenge. Journal of Agricultural and Food Chemistry. 2022
- Metabolomic Profile and Biological Properties of Sea Lavender (Limonium algarvense Erben) Plants Cultivated with Aquaculture Wastewaters: Implications for Its Use in Herbal Formulations and Food Additives. Foods. 2021
- Bioactivity screening of pinhão (Araucaria Angustifolia (Bertol.) Kuntze) seed extracts: the inhibition of cholinesterases and a-amylases, and cytotoxic and anti-inflammatory activities. Food & Function. 2021
- A Case Study on Surplus Mushrooms Production: Extraction and Recovery of Vitamin D2. Agriculture. 2021
- Eggplant Fruit (Solanum melongena L.) and Bio-Residues as a Source of Nutrients, Bioactive Compounds, and Food Colorants, Using Innovative Food Technologies. Applied Sciences. 2021
- Extraction of Anthocyanins from Red Raspberry for Natural Food Colorants Development: Processes Optimization and In Vitro Bioactivity. Processes. 2020
- Hydroethanolic extract of Juglans regia L. green husks: A source of bioactive phytochemicals. Food and Chemical Toxicology. 2020
- Influence of nanoencapsulated lutein on acetylcholinesterase activity: In vitro determination, kinetic parameters, and in silico docking simulations. Food Chemistry. 2020
- Jabuticaba residues (Myrciaria jaboticaba (Vell.) Berg) are rich sources of valuable compounds with bioactive properties. Food Chemistry. 2020
- Hydroethanolic extract of Juglans regia L. green husks: A source of bioactive phytochemicals. Food and Chemical Toxicology. 2020
- Jabuticaba residues (Myrciaria jaboticaba (Vell.) Berg) are rich sources of valuable compounds with bioactive properties. Food Chemistry. 2020
- Phenolic profiling, biological activities and in silico studies of Acacia tortilis (Forssk.) Hayne ssp. raddiana extracts. Food Bioscience. 2020
- Nutritional, chemical and bioactive profiles of different parts of a Portuguese common fig (Ficus carica L.) variety. Food Research International. 2019
- Chemical composition and biological activities of Juçara (Euterpe edulis Martius) fruit by-products, a promising underexploited source of high-added value compounds. Journal of Functional Foods. 2019
- Chemical features and bioactivities of cornflower (Centaurea cyanus L.) capitula: The blue flowers and the unexplored non-edible part. Food Research International. 2019
- Calluna vulgaris (L.) Hull: chemical characterization, evaluation of its bioactive properties and effect on the vaginal microbiota. Food & Function. 2019
- Chemical composition and biological activities of Jucara (Euterpe edulis Martius) fruit by-products, a promising underexploited source of high-added value compounds. Journal of Functional Foods. 2019
- Phytochemical profile and biological activities of 'Ora-pro-nobis' leaves (Pereskia aculeata Miller), an underexploited superfood from the Brazilian Atlantic Forest. Food Chemistry. 2019
- Phytochemical profile and biological activities of 'Ora-pro-nobis' leaves (Pereskia aculeata Miller), an underexploited superfood from the Brazilian Atlantic Forest. Food Chemistry. 2019
- Biological Activities Evaluation of Enantiopure Isoxazolidine Derivatives: In Vitro, In Vivo and In Silico Studies. Applied Biochemistry and Biotechnology. 2018
- Multifunctions of Pleurotus sajor-caju (Fr.) Singer: A highly nutritious food and a source for bioactive compounds. Food Chemistry. 2018
- Antiangiogenic compounds: well-established drugs versus emerging natural molecules. Cancer Letters. 2018
- Apoptosis induction by Pleurotus sajor-caju (Fr.) Singer extracts on colorectal cancer cell lines. Food and Chemical Toxicology. 2018
- Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2. Cell Death & Disease. 2017
- Evaluation of Arenaria montana L. hydroethanolic extract as a chemopreventive food ingredient: A case study focusing a dairy product (yogurt). Journal of Functional Foods. 2017
- A comparison of the bioactivity and phytochemical profile of three different cultivars of globe amaranth: Red, white, and pink. Food & Function. 2016
- Wild Roman chamomile extracts and phenolic compounds: Enzymatic assays and molecular modelling studies with VEGFR-2 tyrosine kinase. Food & Function. 2016
- Synthesis, antiangiogenesis evaluation and molecular docking studies of 1-aryl-3-[(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas: Discovery of a new substitution pattern for type II VEGFR-2 Tyr kinase inhibitors. Bioorganic & Medicinal Chemistry. 2015
- Docking Studies in Target Proteins Involved in Antibacterial Action Mechanisms: Extending the Knowledge on Standard Antibiotics to Antimicrobial Mushroom Compounds. Molecules. 2014
- Antimicrobial activity of phenolic compounds identified in wild mushrooms, SAR analysis and docking studies. Journal of Applied Microbiology. 2013
- 1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR-2 tyrosine kinase inhibitors: Synthesis, biological evaluation, and molecular modelling studies. BioMed Research International. 2013
- ERBB2 in Cat Mammary Neoplasias Disclosed a Positive Correlation between RNA and Protein Low Expression Levels: A Model for erbB-2 Negative Human Breast Cancer. PLOS ONE. 2013
- New di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series: Synthesis, growth inhibitory activity on human tumor cell lines and non-tumor cells, effects on cell cycle and on programmed cell death. European Journal of Medicinal Chemistry. 2013
- Virtual screening of low molecular weight mushrooms compounds as potential Mdm2 inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 2013
- Aminodi(hetero)arylamines in the thieno[3,2-b]pyridine series: Synthesis, effects in human tumor cells growth, cell cycle analysis, apoptosis and evaluation of toxicity using non-tumor cells. Molecules. 2012
- Crataegus monogyna buds and fruits phenolic extracts: Growth inhibitory activity on human tumor cell lines and chemical characterization by HPLC-DAD-ESI/MS. Food Research International. 2012
- Selective Flexibility of Side-Chain Residues Improves VEGFR-2 Docking Score using AutoDock Vina. Chemical Biology and Drug Design. 2012
- ChemT, an open-source software for building template-based chemical libraries. SAR and QSAR in Environmental Research. 2011
- Anti-hepatocellular carcinoma activity using human HepG2 cells and hepatotoxicity of 6-substituted methyl 3-aminothieno[3,2-b]pyridine-2- carboxylate derivatives: In vitro evaluation, cell cycle analysis and QSAR studies. European Journal of Medicinal Chemistry. 2011
- QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition. Chemometrics and Intelligent Laboratory Systems. 2011
- Using molecular docking to investigate the anti-breast cancer activity of low molecular weight compounds present on wild mushrooms. SAR and QSAR in Environmental Research. 2011
- MOLA: A bootable, self-configuring system for virtual screening using AutoDock4/Vina on computer clusters. Journal of Cheminformatics. 2010
- Antioxidants in Wild Mushrooms. Current Medicinal Chemistry. 2009
- Insights in the antioxidant activity of diarylamines from the 2,3-dimethylbenzo[b]thiophene through the redox profile. Journal of Electroanalytical Chemistry. 2009
- A QCAR model for predicting antioxidant activity of wild mushrooms. SAR and QSAR in Environmental Research. 2009
- QSAR model for predicting radical scavenging activity of di(hetero)arylamines derivatives of benzo[b]thiophenes. European Journal of Medicinal Chemistry. 2009
- Stress oxidativo, antioxidantes e fitoquímicos. Bioanálise. 2007
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artigo de conferência
- Bioactivity of the vitamin D2-enriched extract from surplus mushrooms 2022
- Basil and eucalyptus as a source of essential oils with bioactive properties 2022
- Valorization of apple by-products into flour: Nutritional and chemical characterization and evaluation of bioactive properties 2022
- Bio-based hybrid molecules for coloring and preservative purposes 2022
- FIG (Ficus Carica L.) Bioresidues as sources of bioactive compounds and natural pigments for the food industry 2022
- Extraction of bioactive compounds from plants as promising agentes against SARS-CoV-2 2021
- Plants from Lamiaceae family as a source of essential oils with bioactive properties 2021
- Development of semi-solid formulations containing Juglans regia L. leaves extracts for tropical application 2021
- Optimization and recovery of Vitamin D2 from spurplus production of Agaricus bisporus Portobello. 1st Natural products application: Health, Cosmetic and Food. 2021
- RED RASPBERRY WASTE AS A SOURCE OF ANTHOCYANIN-RICH FOOD COLORANTS: EXTRACTION PROCESS OPTIMIZATION AND FUNCTIONALITY ASSESSMENT 2021
- Composição Química e Atividades Biológicas da Casca do Fruto da Palmeira Juçara (Euterpe edulis Martius) 2019
- Perfil fitoquímico e atividades biológicas das folhas de "Orapronóbis" (Pereskia aculeata Miller) 2019
- Chemical composition and bioactivities of Juçara fruit bio-residues, a promising source of valuable molecules 2019
- Composition in anthocyanins and bioactive properties of jabuticaba bioresidues. XX EuroFoodChem Conference. 2019
- Farnesoid X Receptor as a potential protein target for mushroom LMW compounds: virtual screening using molecular docking 2017
- Investigating mushroom LMW compounds as potential Bcl-2 inhibitors: docking studies using AutoDock4 2016
- Antioxidant and anti-inflammatory properties of red, white and pink globe amaranth hydromethanolic extracts 2015
- A amilóide A no leite é útil no diagnóstico de mastites subclínicas em caprinos? 2015
- Anti-inflammatory activity of mushrooms extracts, identified phenolic acids and their possible metabolites 2015
- Inhibition of the VEGFR-2 tyrosine kinase domain by witd Roman chamomile extracts and phenolic compounds 2015
- VScore: a software for management of large scale virtual screening projects in computer clusters 2015
- Diagnóstico de mastite subclínica caprina pelo método do doseamento de Amilóide A no leite 2014
- Diagnóstico de mastites subclínicas caprinas pelo método do doseamento de Amilóide A do leite 2014
- New di(hetero)aryl)ethers and Di(hetero)arylamines in the thieno[3,2-b]pyridine series: synthesis, growth inhibitory activity on tumor cell lines and non tumor cells, effects on cell cycle and on apoptosis 2014
- Synthesis, molecular Docking and biological evaluation of new 1-Aryl-3-[3-(thieno[3,2-b]pyridin-7-ylthio)phenylureas as Potent Type II VEGFR-2 Tyrosine Kinase inhibitors 2014
- Virtual screening of thieno[3,2-b]pyridine arylthioether (hetero)aryltriazole derivatives as potential tyrosine kinase VEGFR2 inhibitors.. XIX Encontro Galego-Português de Química. 2013
- Synthesis of new n-[3-(thieno[3,2-b]pyridine-7-ylthio)phenyl]benzamides as potential inhibitors of VEGFR2 using rational design 2013
- Aplicação de ferramentas de quimioinformática no desenvolvimento de novos fármacos: tienopiridinas como inibidores de VEGFR-2 2013
- Epidermal growth factor receptor inhibitory activity of new potential antitumor di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series 2013
- Evaluation of growth inhibitory activity of Crataegus monogyna Jacq. flower bud extracts against human tumor cell lines 2013
- New di(heteroaryl)thioethers 1,3-diarylureas in the thieno[3,2-b]pyridine series as VEGFR2 tyrosine kinase inhibitors: docking, synthesis, enzymatic and cellular assays 2013
- Synthesis and evaluation of the antitumor potential of new aminated or methoxylated di(hetero)arylthioethers in the thieno[3,2-b]pyridine series 2013
- Synthesis of new N-[3-(thieno[3,2-b]pyridine-7-ylthio)phenyl]benzamides as potential inhibitors the tyrosine kinase domain of VEGFR2 2013
- VScore: uma plataforma para desenvolvimento de novos fármacos usando screening virtual 2013
- Heteroarylether 1,3-diarylureas in the thieno[3,2-d]pyrimidine series as VEGFR2 tyrosine Kinase inhibitors: Synthesis, docking studies, enzymatic and cellular assays 2012
- Synthesis, growth inhibitory activity on human tumor cell lines and evaluation of the hepatotoxicity of di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series. 2012
- 1-Aryl-3-[ 4-( thieno[3,2-d]pyrimidin-4-yloxy )phenyl]ureas as VEG FR2 inhibitors: synthesis, docking enzymatic and cellular assays 2012
- 1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 tyrosine kinase inhibitors: synthesis, docking studies, enzymatic and cellular assays 2012
- Docking studies to evaluate mushrooms low molecular weight compounds as inhibitors of the anti-apoptotic protein BCL-2 2012
- Screening virtual e dinâmica molecular de compostos presentes em cogumelos com potencial inibidor de BCL2 2012
- Synthesis of novel 1-aryl-3-[2,3- or 4-(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas and evaluation as VEGFR2 tyrosine kinase inhibitors 2012
- Synthesis, docking, enzymatic and cellular assays of thieno[3,2-b]pyridine-thioether-1,3-diarylureas as VEGFR2 inhibitors 2012
- Thieno[3,2-b]pyridine arylethers: synthesis and growth inhibitory activity on human tumor cell lines 2012
- 1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as potential inhibitors of VEGFR-2: synthesis and molecular modelling studies 2011
- 1-aryl-3-(4-(7-methylthieno[3,2-d]pyrimidin-4-yloxy)phenyl)ureas: synthesis and molecular modelling studies using VEGFR-2 2011
- Chemical, biochemical and electrochemical assays to evaluate antioxidant properties of three new diarylamines in the thieno[3,2-b]pyridine series. 2011
- Desenvolvimento de ferramentas de bioinformática para aplicação em Química Medicinal: MOLA e ChemT. 2011
- Mdm2 as a potential target for mushrooms LMW compounds. 2011
- Methyl 3-[4-(3-arylureido)phenylamino]thieno[3,2-b]pyridine-2-carboxylates as potential inhibitors of VEGFR-2: synthesis and molecular modelling studies 2011
- Methyl 3-amino-6-[4 or 3 or 2-(3-arylureido)phenyl]thieno[3,2-b]pyridine-2-carboxylates: synthesis and molecular modelling studies using VEGFR-2 2011
- New potential anti-hepatocellular carcinoma (HCC) agents: in vitro evaluation of anti-HCC activity and hepatotoxicity of 6-substituted methyl 3-aminothieno[3,2-b]pyridine-2-carboxylates and QSAR studies 2011
- Rational design of thieno[3,2-b]pyridines as potential new VEGFR-2 inhibitors based on improved docking scores. 2011
- Synthesis of aminodiarylamines in the thieno[3,2-b]pyridine series and effects on tumor cell growth inhibition, cell cycle and apoptosis 2011
- VEGFR2 selective residue flexibility enriches AutoDock Vina docking results 2011
- Valorização de cogumelos silvestres como alimentos funcionais: estudos de química computacional 2011
- Anti-proliferative activity of thieno[3,2-b]pyridine derivatives in tumoral and primary hepatic cell lines. 2010
- ChemT, a software for building template-based 3D chemical libraries. 2010
- Docking studies using proteins involved in breast cancer and low molecular weight compounds found in wild mushrooms 2010
- Virtual ligand screening studies between mushroom compounds and proteins involved in breast cancer 2010
- MOLA: a tool for automation of parallel virtual docking using AutoDock Vina in a heterogeneous set of computer clusters 2009
- Nova metodologia computacional de “Docking” proteína-ligando utilizando o AutoDock4 2009
- O potencial antioxidante dos fitoquímicos 2008
- A convenient high performance computing (HPC) methodology for virtual screening using Autodock 4 2008
- Electrochemical evaluation of the redox-properties of diarylamines in the 2,3-dimethylbenzo[b]thiophene series 2008
- Farnesoid X receptor: docking model validation 2008
- Interference of environmental factors in serum bilirubin levels - a preliminary study 2008
- New methoxylated di(hetero)arylamines derivatives of a thienopyridine: synthesis and antioxidant activity using different methods 2008
- QSAR studies on di(hetero)arylamines derivatives of benzo[b]thiophenes as free radical scavengers 2008
- Synthesis and antioxidant activity of new methoxylated di(hetero)arylamines derivatives of thieno[3,2-b]pyridines, 2008
- Ground-cover systems in non-irrigated olive orchards 2006
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capítulo de livro
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poster de conferência
- Proposal for the Development of Bio Based Hybrid Molecules: Exploring Molecular Dynamics for Coloring and Preservation of Molecules 2025
- Exploring Molecular Dynamics for the Development of Bio-based Hybrid Molecules With Applications in Coloring and Preservation 2024
- Virtual screening of a library of natural compounds against COX-2 protein 2022
- Diagnóstico de mastites subclínicas caprinas pelo método do doseamento de Amilóide A do leite 2014
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documento
- Bioaccessible Profile Of Polyphenols From Up4health's Olive Pomace Based Ingredient: Sustainability And Healthiness Converging In The Agrifood Sector 2024
- Up4Health ingredients: speciality plant-based food processing by-products extracts for industrial application 2023
- Molecular dynamics studies targeting coloring and preserving molecules: proposal for the development of bio-based hybrid molecules 2022
- Nutritional and bioactive characterization of Apium graveolensis. L. 2022
- Chromatographic profile of free sugars in fruits from five different varieties of Ficus carica L.. 2022
- Fig (Ficus carica L.) biowaste as sources of phenolic compounds for the food and pharmaceutical industry. 2022
- FIG (FICUS CARICA L.) Synergic aspects between biotechnology and computer science 2022
- Optimization of Total Phenolic Content of Fig Leaves Obtained Through Response Surface Methodology. 2022
- Optimization of total phenolic content of fig obtained through Response Surface Methodology 2022
- Nutritional and bioactive characterization of Apium graveolensis. L. 2021
- Predominant phenolic compounds in Mountain plants with possible antiviral potential against SARS-CoV2 2021
- Antimicrobial and cytotoxic activity of Amaranthaceae famyly extract: source of new antibiotics and anticancer treatments 2021
- Red Raspberry waste as a source of anthocyanin-rich food colorants: extraction process optimization and functiobality assessment 2021
- Phytochemical profile and biological activities of "Ora-pro-nobis" leaves (Pereskia aculeata Miller), an underexploited superfood from the Brazilian Atlantic Forest 2019
- Jabuticaba (Myrciaria jaboticaba (Vall.) O. Berg) residue as a source of bioactives molecules 2019
- Antiangiogenic effects of new di(hetero)arylthioethers 1,3-diarylureas in the thieno[3,2-b]pyridine series. Role in VEGFR-2 inhibition. 2013
- New di(hetero)arylthioethers 1,3-diarylureas in the thieno[3,2-b]pyridine series as VEGFR2 tyrosine kinase Inhibitors: docking, synthesis, enzymatic and cellular assays 2013
- New di(heteroaryl)thioethers 1,3-diarylureas in the thieno[3,2-b]pyridine series as VEGFR-2 tyrosine kinase inhibitors: docking, synthesis, enzymatic and celular assay. 2013
- 1-Aryl-3-[4-(thieno[3,2-b]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 inhibitors: synthesis, docking, enzumatic and celular assays 2012
- Synthesis, growth inhibitory activity on human tumor cell lines and evaluation of the hepatotoxicity of di(hétero)arylethers and di(hétero)arylamines in the thieno[3,2-b]pyridine series 2012
- Synthesis of novel 1-ary-3-[2-, 3- or 4-(thieno[3,2-b]pyridin-7-ylyhio)phenyl]ureas and evaluation as VEGFR2 tyrosine kinase inhibitors 2012
- Thieno [3,2-b]pyridine arylethers: synthesis and growth inhibitory activity on human tumor cell lines 2012
- Docking studies to evaluate the potential capacity of mushrooms low molecular weight compounds as inhibitors of the anti-apoptotic protein Bcl-2 2012