Thieno[3,2-b]pyridine arylethers: synthesis and growth inhibitory activity on human tumor cell lines
Artigo de Conferência
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resumo
Thienopyridine skeleton has been reported as havi ng inte resting
biological activity, namely antitumorlll and antiangiogenic121
activities. Herein, we describe the synth esis of thienopyridine arylethers
la-f in moderate to good yields by a copper-cata lyzed
C- 0 coupling, using N,N-dimethylglycine as a ligand, of the
7-bromothieno[3,2-b]pyridine, also prepared with substituted
phenols (see scheme).
