selected publications
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academic article
- First intramolecular Diels–Alder reactions using chromone derivatives: synthesis of chromeno[3,4-b]xanthones and 2-(benzo[c]chromenyl)chromones. New Journal of Chemistry. 2018
- Hepatoprotective activity of polyhydroxylated 2-styrylchromones against tert-butylhydroperoxide induced toxicity in freshly isolated rat hepatocytes. Archives of Toxicology. 77:500-505. 2003
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conference paper
- Chromones as versatile building blocks in cycloaddition reactions. 233. 2017
- Conjugate additions of carbon nucleophiles to chromone derivatives towards nitrogen heterocycles 2017
- Conjugate additions of carbon nucleophiles to chromones substituted with extended p-systems at C-2 2017
- Conjugate additions of carbon nucleophiles to chromones substituted with extended π-systems at C-2. 128. 2017
- Microwave-assisted synthesis of chromeno[3,4-b]xanthones and (benzo[c]cromenyl)chromones. 118. 2017
- Nitromethane conjugate addition to 2-[(1E,3E)-4-arylbuta-1,3-dien-1-yl]-4Hchromen- 4-ones 2017
- 2-[(1E,3E)-4-Arylbuta-1,3-dien-1-yl]-4H-chromen-4-ones as dienes in Diels–Alder reactions: experimental and computational studies 2016
- Chromone derivatives as novel dienes in Diels-Alder reactions 2016
- Recent developments in the synthesis of novel xanthone-1,2,3-triazole dyads 2015
- Synthesis of xanthone-1,2,3-triazole dyads 2015
- 2-(4-Arylbuta-1,3-dien- or 1-en-3-yn-1-yl)chromones as synthons for the synthesis of other nitrogen and oxygen heterocyclic compounds 2014
- Síntese de novas cromonas e xantonas com atividade captadora de espécies reativas de oxigénio. 384. 2014
- Synthesis of (E)-2-(4-Arylbut-1-en-3-ynyl)-4H-chromen-4-ones. 63. 2013
- Synthesis of 2-{2-[5(4)-aryl-2H-[1,2,3]-triazol-4(5)-yl]vinyl}chromen-4-ones. 103. 2013
- Electrochemical characterization of hydroxylated xanthones by cyclic voltammetry 2012
- New syntheses of novel arylxanthones 2012
- Polyhydroxylated 2-styrylchromones and –xanthones as potent antioxidante agentes 2012
- Structure determination of some oxygen and nitrogen heterocyclic compounds by NMR 2012
- Synthesis of novel 2-Butadienylchromone derivatives 2012
- Novel Hydroxy-9H-xanthen-9-ones derivatives: synthesis and bioactive properties 2011
- Metodologias para avaliar a actividade captadora de espécies reactivas de oxigénio e de azoto envolvidas no processo inflamatório 2010
- NDPO2 as a selective generator of 1o2 used in the scavenging activity assay of 2,3-diarylxanthones 2010
- ROS and RNS Scavenging Activity by 2,3-Diarylxanthones 2010
- Recent developments in the synthesis of 1-aryl-9H-xanthen-9-ones 2010
- Studies towards the synthesis of polyhydroxyxanthones with potential antioxidant activity 2010
- The 2-styrylchromone structure is an effective scaffold for the development of new inibitors of the nf-kb pathway 2010
- Anti-inflammatory potencial of 2-Styrylchromones regarding their interference with arachidonic acid metabolic pathways 2008
- Cyclic voltammetric analysis of 2-styrylchromones 2008
- Incorporation of 2-styrylchromones in liposomes: preliminaries studies 2008
- Novel 2-Styrylchromones with high anti-inflammatory potencial through prevention of LTB4 production by human leukocytes, inhibition of COX-1 activity and scavenging of ROS and RNS 2008
- Polyhydroxy-2,3-diarylxanthones as antioxidants 2008
- The ROS and RNS scavenging activity of 2-Styrylchromones are effectively repreoduced by cyclic voltammetry analysis 2008
- Inhibition of Leukotriene B4 production in human Neutrophils by 2-Styrylchromones 2007
- Interactions of 2-Styrylchromones with pro-inflamatory enzymes and oxidative species 2007
- Polyhydroxy-2,3-Arylxanthones: a total synthesis 2007
- A novel route for the synthesis of 2,3-Diarylxanthones 2006
- Epoxidation of (E,E)-Cinnamylideneacetophenones Using Salen Mn(III) as Catalyst 2006
- NMR in the epoxidation of (E,E)-Cinnamylideneacetophenones 2006
- Singlet oxygen scavenging activity by 2-Styrylchromones 2006
- Synthesis of 2,3-Arylxanthones using palladium catalysts 2006
- Synthesis of Polyhydroxy-2,3-diarylxanthones with potencial antioxidant activity 2006
- Nitric oxide and superoxide radical scavenging of 2-Styrylchromones 2005
- Synthesis of 2,3-Distyrylchromones 2005
- Synthesis of new xanthone derivatives 2005
- Epoxidation of 2-Styrylchromone derivatives 2004
- Epoxidação de (E,E)-Cinamilidenoacetofenonas com Peróxido de Hidrogénio 2004
- Epoxidation Studies do 2-Styrylchromones 2003
- Hepatoprotective activity of 2-styrylchromone derivatives against the pro-oxidant hepatotoxic effect elicited by tert-butylhydroperoxide in freshy isolated rat hepatocytes 2003
- Potent Inhibition of Xanthine Oxidase by Novel 2-Styrylchromones 2001
- 2-Styrylchromones with potencial antioxidant activity 2000
- NMR studies on the antiradical mechanism of phenolic compounds towards 2,2-diphenil-1-pycridrazyl radical 2000
- Synthesis and evaluation of the antiradicalar activity of polyhydroxy-2-styrylchromones 2000
- Synthesis of 2-styrylchromones with potencial antioxidant activity 1999
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journal article
- First intramolecular Diels-Alder reactions using chromone derivatives: Synthesis of chromeno[3,4-: B] xanthones and 2-(benzo [c] chromenyl)chromones. New Journal of Chemistry. 2018
- 1,6-Conjugate Additions of Carbon Nucleophiles to 2-[(1E ,3E )-4-Arylbuta-1,3-dien-1-yl]-4H -chromen-4-ones. European Journal of Organic Chemistry. 5293-5305. 2017
- 2-[(1E ,3E )-4-Arylbuta-1,3-dien-1-yl]-4H -chromen-4-ones as Dienes in Diels-Alder Reactions - Experimental and Computational Studies. European Journal of Organic Chemistry. 87-101. 2017
- (E)-2-(4-Arylbut-1-en-3-yn-1-yl)chromones as Synthons for the Synthesis of Xanthone-1,2,3-triazole Dyads. European Journal of Organic Chemistry. 4732-4743. 2015
- Inhibition of NF-kB Activation and Cytokines Production in THP-1 Monocytes by 2-Styrylchromones. Medicinal Chemistry. 560-566. 2015
- Chalcones as versatile synthons for the synthesis of 5- and 6-membered nitrogen heterocylces. Current Organic Chemistry. 2750-2775. 2014
- Tetrahydroquinazoline-substituted chromones from Diels-Alder reaction of (E)-2-styrylchromones and pyrimidine ortho-quinodimethane. Tetrahedron Letters. 2722-2725. 2012
- Structure-activity relationships in hydroxy-2,3-diarylxanthone antioxidants. Fast kinetics spectroscopy as a tool to evaluate the potential for antioxidant activity in biological systems. Organic and Biomolecular Chemistry. 3965-3974. 2011
- Synthesis of Novel 1-Aryl-9H-xanthen-9-ones. Synlett. 1403-1406. 2011
- 2,3-Diarylxanthones as strong scavengers of reactive oxygen and nitrogen species: A structure-activity relationship study. Bioorganic & Medicinal Chemistry. 6776-6784. 2010
- Anti-inflammatory potential of 2-styrylchromones regarding their interference with arachidonic acid metabolic pathways. Biochemical Pharmacology. 171-177. 2009
- Dimethyldioxirane oxidation of exocyclic (E,E)-cinnamylideneketones. Australian Journal of Chemistry. 82-89. 2009
- Efficient syntheses of new polyhydroxylated 2,3-diaryl-9H-xanthen-9-ones. European Journal of Organic Chemistry. 2642-2660. 2009
- Cyclic voltammetric analysis of 2-styrylchromones: Relationship with the antioxidant activity. Bioorganic & Medicinal Chemistry. 7939-7943. 2008
- 2-Styrylchromones: Novel strong scavengers of reactive oxygen and nitrogen species. Bioorganic & Medicinal Chemistry. 6027-6036. 2007
- A novel and efficient route for the syntheses of hydroxylated 2,3-diarylxanthones. Synlett. 3113-3116. 2007
- Epoxidation of (E,E)-cinnamylideneacetophenones with hydrogen peroxide and iodosylbenzene with salen-MnIII as the catalyst. European Journal of Organic Chemistry. 2877-2887. 2007
- Epoxidation studies of 2-styrylchromones using Jacobsen's catalyst and hydrogen peroxide and iodosylbenzene as oxidants. Journal of Heterocyclic Chemistry. 1319-1326. 2006
- New Synthesis of 2,3-Diarylxanthones. Synlett. 3095-3098. 2005
- Hepatoprotective activity of polyhydroxylated 2-styrylchromones against tert-butylhydroperoxide induced toxicity in freshly isolated rat hepatocytes. Archives of Toxicology. 500-505. 2003
- Synthesis of New Hydroxy-2-styrylchromones. European Journal of Organic Chemistry. 4575-4585. 2003
- 2-Styrylchromones as novel inhibitors of xanthine oxidase. A structure-activity study. Journal of Enzyme Inhibition and Medicinal Chemistry. 45-48. 2002