Purpose Rubus idaeus cultivation has boosted productivity due to its high nutritional value. In consequence, waste produc-
tion increased. The discarded biomass, including leaves and aerial components, can be transformed into valuable functional
ingredients for industrial applications, such as cosmetics. Studying their bioactivity potential is highly relevant.
Methods According to the present idea, the research involved producing extracts from raspberry plant branches and leaves
by employing four different techniques: aqueous decoction, aqueous infusion, hydroethanolic maceration, and ultrasound-
assisted extraction (UAE). Subsequently, these compounds were screened for their bioactive potential, including antioxidant,
antibacterial, anti-inflammatory, and cytotoxic properties.
Results The ultrasound-assisted extraction produced extracts rich in phenolic compounds, whereas the infusion and macera-
tion methods resulted in higher flavonol contents. Among the identified phenolic compounds, hydrolyzable tannins, particu-
larly galloyl-bis-HHDP-glucose, were the most dominant ones. Regarding antioxidant potential, the decoction extract was
the strongest, while the infusion showed the greatest potential for inhibiting lipid peroxidation. The UAE extract was found
to be highly effective as an antibacterial agent. Both infusion and UAE extracts demonstrated the highest anti-inflammatory
potential.
Conclusion The combination of these results highlights the sample’s bioactive potential and the importance of exploiting
bioresidues as unique, sustainable candidates for industrial applications.
