Comparative study of the phenolic profile and antioxidant properties of Chamaemelum nobile: infusion, decoction, and hydroalcoholic extract
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abstract
This stud} aimed to determine the phenolic composition and to evaluate the antioxidant activity
o f different preparation' of Roman chamomile: infusion. decoction and methanol: water (80:20)
extract. The hydroalcoholic extract revealed the highest antioxidant activity in almost all the
performed assays (EC\ , ≤0.62 mg/ml. depending on the assay ). which was in agreement with
its highest total content in phenolic compounds. Otherwise. decoctions presented the lowest
antioxidant potential (EC50 ≤1.4S mg/mL. depending on the assay). The phenolic profile of the
different preparations was identical. varying only in the concentrations found. Phenolic acids
(caffooylquinic acids). flavonols (quercetin and kaempferol derivatives) and flavones (apigenin
and luteolin derivatives) were found in the three preparations. The most abundant compounds in
the infusion and hydroalcoholic ex tract we re 5-0 -caffeoylquinic acid and an apigenin
derivative. These. as also the other phenolic compounds, decreased significantly in the
decoction .
