publicações selecionadas
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artigo de revista
- Wild Roman chamomile extracts and phenolic compounds: Enzymatic assays and molecular modelling studies with VEGFR-2 tyrosine kinase. Food & Function. 2016
- Synthesis, antiangiogenesis evaluation and molecular docking studies of 1-aryl-3-[(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas: Discovery of a new substitution pattern for type II VEGFR-2 Tyr kinase inhibitors. Bioorganic & Medicinal Chemistry. 2015
- Docking Studies in Target Proteins Involved in Antibacterial Action Mechanisms: Extending the Knowledge on Standard Antibiotics to Antimicrobial Mushroom Compounds. Molecules. 2014
- Virtual screening of low molecular weight mushrooms compounds as potential Mdm2 inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 2013
- QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition. Chemometrics and Intelligent Laboratory Systems. 2011
- Using molecular docking to investigate the anti-breast cancer activity of low molecular weight compounds present on wild mushrooms. SAR and QSAR in Environmental Research. 2011
- MOLA: A bootable, self-configuring system for virtual screening using AutoDock4/Vina on computer clusters. Journal of Cheminformatics. 2010
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artigo de conferência
- Inhibition of the VEGFR-2 tyrosine kinase domain by witd Roman chamomile extracts and phenolic compounds 2015
- Synthesis of new n-[3-(thieno[3,2-b]pyridine-7-ylthio)phenyl]benzamides as potential inhibitors of VEGFR2 using rational design 2013
- VScore: uma plataforma para desenvolvimento de novos fármacos usando screening virtual 2013
- 1-Aryl-3-[ 4-( thieno[3,2-d]pyrimidin-4-yloxy )phenyl]ureas as VEG FR2 inhibitors: synthesis, docking enzymatic and cellular assays 2012
- Screening virtual e dinâmica molecular de compostos presentes em cogumelos com potencial inibidor de BCL2 2012
- Desenvolvimento de ferramentas de bioinformática para aplicação em Química Medicinal: MOLA e ChemT. 2011
- Mdm2 as a potential target for mushrooms LMW compounds. 2011
- Valorização de cogumelos silvestres como alimentos funcionais: estudos de química computacional 2011
- ChemT, a software for building template-based 3D chemical libraries. 2010
- Docking studies using proteins involved in breast cancer and low molecular weight compounds found in wild mushrooms 2010
- Virtual ligand screening studies between mushroom compounds and proteins involved in breast cancer 2010
- Nova metodologia computacional de “Docking” proteína-ligando utilizando o AutoDock4 2009
- Farnesoid X receptor: docking model validation 2008
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documento
- Synthesis of new N-[3-(thieno[3,2-b]pyridine-7-ylthio)phenyl]benzamides as potential inhibitors the tyrosine kinase domain of VEGFR2 2013
- 1-Aryl-3-[4-(thieno[3,2-b]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 inhibitors: synthesis, docking, enzumatic and celular assays 2012
- Synthesis of novel 1-ary-3-[2-, 3- or 4-(thieno[3,2-b]pyridin-7-ylyhio)phenyl]ureas and evaluation as VEGFR2 tyrosine kinase inhibitors 2012
- Docking studies to evaluate the potential capacity of mushrooms low molecular weight compounds as inhibitors of the anti-apoptotic protein Bcl-2 2012
- Heteroarylether 1,3-diarylureas in the thieno[3,2-d]pyrimidine series as VEGFR2 tyrosine Kinase inhibitors: Synthesis, docking studies, enzymatic and cellular assays 2012
- 1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 tyrosine kinase inhibitors: synthesis, docking studies, enzymatic and cellular assays 2012
- Methyl 3-[4-(3-arylureido)phenylamino]thieno[3,2-b]pyridine-2-carboxylates as potential inhibitors of VEGFR-2: synthesis and molecular modelling studies 2011
- Rational design of thieno[3,2-b]pyridines as potential new VEGFR-2 inhibitors based on improved docking scores. 2011
- O potencial antioxidante dos fitoquímicos 2008