A new microfluidic methodology to assess the haemocompatibility of magnetic nanoparticles designed for theranostic applications
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abstract
The remarkable physicochemical properties of magnetic nanoparticles (MNPs) at the
nanoscale have boosted the development of new and promising strategies for the simultaneous
diagnosis and treatment of diseases, particularly in cancer therapy Ð the so-called theranostic
applications (1). In these strategies, the intrinsic superparamagnetic properties of MNPs have
been exploited to gain access into multifunctional systems able to simultaneously perform
as enhanced magnetic resonance imaging (MRI) contrast agents, efficient nanocarriers for
drug delivery and nanoheaters in magnetic hyperthermia based therapy (2), among others.