Portable ECG/sEMG acquisition systems for telemedicine often lack application flexibility (e.g., limited configurability, signal validation) and efficient wireless data handling. A modular biosignal acquisition system with up to 8 channels, 24-bit resolution and configurable sampling (1–4 kHz) is proposed, featuring per-channel gain/source adjustments, internal MUX-based reference drive, and visual electrode integrity monitoring; Bluetooth® transmits data via a bit-wise packet structure (83.92% smaller than JSON, 7.28 times faster decoding with linear complexity based on input size). Results: maximum 6.7 μVrms input-referred noise; harmonic signal correlations >99.99%, worst-case THD of -53.03 dBc, and pulse wave correlation >99.68% in frequency-domain with maximum NMSE% of 6e-6%; and 22.3-hour operation (3.3 Ah battery @ 150 mA).
The system enables high-fidelity, power-efficient acquisition with validated signal integrity and adaptable multi-channel acquisition, addressing gaps in portable biosensing.