Radical scavenging activity, lipid peroxidation inhibition and redox profile of aminodiarylamines in the thieno[3,2-b]pyridine series
Conference Paper
Overview
Overview
abstract
FCT for financial support through the NMR Portuguese network (Bruker 400 Avance 111-Univ Minho).
To FCT and FEDER-COMPETE/QREN/EU for financial support through the research unities PEstC/
QUI/UI686/2011 and PEst-OE/AGR/UI0690/2011 , the research project PTDC/QUI-QUI/111 060/2009
and the post-Doctoral grant attributed to R.C.C. (SFRH/SPD/68344/201 0) also financed by POPH and
FSE.
The reducing properties of diarylamines make them very important as antioxidants, especially as
radical scavengers as it has been demonstrated by our and other research groups [1 -3]. Three
di(hetero)arylamines were prepared by C- N coupling of the methyl3-amino-6-bromothieno(3,2-
b]pyridine-2-carboxylate with bromonitrobenzenes and further reduced to the amino compounds 1a-c
(Scheme) (4].
