Non-Alkaloid Nitrogen Containing Compounds from Fungi Chapter uri icon

abstract

  • Fungi represent an ancient ubiquitous and interesting kingdom that can be classified into Phycomycota, Oomycota, Microsporidiomycota, Zygomycota, Ascomycota, Basidiomycota, and Deuteromycota divisions. These microorganisms are considered as a reservoir of bioactive compounds that can be exploited in crucial fields: food, pharmaceutical, and agricultural industries. Non-alkaloid nitrogenated compounds are considered a prolific bouquet composed of proteins such as enzymes playing an essential role in the synthesis of compounds that are involved in vital life processes, lytic enzymes possessing depleting effects, antibiotics, toxins applied as antimicrobials and antifungals, immunosuppressive molecules, etc. Moreover, a number of species found in phyla like Oomycota and Microsporidiomycota have been and are still used as biological control agents for crops as a counterpart to chemical products.
  • The research leading to these results was supported by MICINN supporting the Ramón y Cajal grant for M.A. Prieto (RYC-2017-22891), the post-doctoral grant of M. Fraga- Corral (ED481B-2019/096), and L. Cassani (ED481B-2021/152), and the pre-doctoral grant of A.G. Pereira (ED481A-2019/0228). Authors are grateful to Ibero-American Program on Science and Technology (CYTED-AQUA-CIBUS, P317RT0003), to the Bio Based Industries Joint Undertaking (JU) under grant agreement No 888003 UP4HEALTH Project (H2020-BBI-JTI-2019). The JU receives support from the European Union’s Horizon 2020 research and innovation program and the Bio Based Industries Consortium. The project SYSTEMIC Knowledge hub on Nutrition and Food Security, has received funding from national research funding parties in Belgium (FWO), France (INRA), Germany (BLE), Italy (MIPAAF), Latvia (IZM), Norway (RCN), Portugal (FCT), and Spain (AEI) in a joint action of JPI HDHL, JPI-OCEANS and FACCE-JPI launched in 2019 under the ERA-NET ERA-HDHL (n° 696295). The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES to the CIMO (UIDB/00690/2020). I. Oliveira thanks FCT for her PhD grant (BD/06017/2020). M. Carocho thanks FCT for his individual scientific contract (CEEC-IND/00831/2018).

publication date

  • 2023