Experiments on computer assisted optimization of the escherichia coli fermentation process using Optferm Conference Paper uri icon

abstract

  • We used the software Optferm to model and optimize the bioprocess of escherichia coli fermentation, simulating the conditions of a fed-batch bioreactor. The results, obtained by employing different AI approaches, provided useful orientation for nutrient feed strategies for increased productivity. In conclusion, we believe in silico tools can perform a rapid and valid optimization of bioprocesses avoiding expensive experiments.

publication date

  • January 1, 2011